Irritable Bowel Syndrome (IBS) is a chronic functional intestinal disease that can be divided into diarrhea type (D-IBS), constipation type (C-IBS), mixed type (M-IBS), and atypical type (U-IBS) based on its clinical manifestations, with diarrhea type being the most common. The establishment of a diarrhea type irritable bowel syndrome model is of great significance for studying the pathophysiology, pathogenesis, and drug treatment of the disease.

Observation indicators

Fecal trait score, fecal water content, abdominal wall withdrawal reflex (AWR) score, colon pathology examination, etc;